Treatment of Early Menopause Can Improve Ovarian Function and Restore Fertility

Planning your family later years, like after 40, is now possible thanks to new treatments for early menopause. It’s a sign of courage for women who face fertility problems due to early menopause. Although the treatments still need more research and advancement to provide better results on a larger scale, the hope is there.

The records show that US women find it more convenient to start their families after 40. But they find it difficult because of early menopause. However, the birth rate is rising in women of ages 40 to 45 in the last few years, a healthy sign.

Many women planned to become mothers in their forties, but they couldn’t do it because of early menopause. So, they had to go for a donor egg to make birth possible.

However, Everyday Health’s story suggests how modern treatments can help restore fertility in women above 40. 

It Is Possible for Women with Early Menopause to Restore Fertility

A study published in the journal menopause suggests that restoring fertility after early menopause is possible. The authors claimed that gonadotropins near ovarian follicles and platelet-rich plasma might help to reactivate ovaries. Therefore, it will help start menstruation cycles in women and restore fertility.

Since this process reboots the ovarian function, it will be possible for women to give birth using their eggs. Ovarian failure and menopause stop the production of new eggs in the ovaries. A Ph.D. explained the process. Chao Chin Hsu.

What Is Early Menopause and Who is at Risk?

Menopause is the skipping of the menstrual cycle for one year. It usually happens in the late forties and early fifties, as explained by Stephanie S Faubion. She works as the director of the Centre for Women’s Health in Mayo clinic.

Stephanie explains that early menopause starts before or at the age of forty. However, many of the women hide it and do not record it. It usually happens in women who use birth control pills.

Whereas menopause only becomes official when it happens naturally when there are no hormonal treatments and pills involved.

Age Ranges for Early Menopause and Typical Menopause

Experiencing menopause after the age of 46 is normal, and it happens naturally. While several women experience it in their early forties, some of them may experience it before forty—the latter experience early or premature menopause

Since premature menopause isn’t ideal for aspiring mothers, the percentage of women that experience it is considerably high. Currently, six percent of women in the US go through early menopause, says Stephanie S Faubion.

Signs of Early Menopause

The signs that show early menopause are;

  • Bleeding stops for more than a year
  • POI (Premature Ovarian Insufficiency)
  • Spontaneous periods periodically but pregnancy is possible meanwhile
  • Hot flashes
  • Infertility or inability to conceive
  • Sweating
  • Genitourinary syndrome happens due to hormone imbalance
  • Dryness and irritation
  • Lack of lubrication
  • Pain and discomfort
  • Urgency in urination (UTI) 

In POI, there is only spotting, or the menstrual cycle happens after every three months. While investigating POI, it is seen that the hormone which shows the amount of viable follicle in ovaries is deficient.

Dr. Stephanie says that while POI happens, there might be no other symptoms of early menopause except missed periods.

It Is Possible to Resume Periods While Experiencing Menopause

The study includes women who had missed their periods for a year. They were experiencing early menopause at an average age of 44. The study didn’t include cancer patients exposed to chemotherapy radiation and women who had got the ovarian tissue removed through surgery.  

The platelets-rich plasma along with gonadotropins was injected into the ovaries of volunteers to see the results. More than 90% of the participants resumed their menstrual cycle.

The doctors injected the selected sperm directly into the egg. Surprisingly, one of the six participants recorded clinical pregnancy.

Is the Use of Gonadotropins and Platelet-Rich Plasma Possible for Every Woman?

More research is needed to use these two agents generally for every woman facing early menopause and infertility. Currently, it is tested upon those who are in clinical trials. 

As Dr. Faubion says, it is too early to estimate the whole process’s actual cost since the price of donor eggs is very high in the US.

Early Menopause Treatment is Possible

The experts recorded the restoration of ovarian hormone and improved follicle growth in the women who got the treatment. Hence it is possible to treat early menopause with platelet-rich plasma, according to Dr.Hsu.

Early menopause can have adverse outcomes as you grow older. That may include;

  • Cardiovascular disorders
  • Osteoporosis
  • Fracture
  • Cognitive disabilities
  • Depression
  • Dementia
  • Telomere shortening (accelerated aging)
  • Early death.

Ovarian Health is Important

Ovarian health completes a woman. It has many other benefits besides fertility. Therefore, restoring it has enormous benefits on the overall health of a woman. 

Furthermore, it slows down aging in women and helps eliminate many health issues and diseases that may lead to early death.

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What’s the Next Step?

Dr.Faubion believes that platelet-rich plasma might not have long-lasting effects if given over a shorter time. Yet, there is a need for more studies on a larger scale to evaluate its long-lasting benefits. Here is what’s needed

  • Studies on a more significant number of women with early menopause symptoms.
  • It is essential to examine the root causes of early menopause to eliminate the issue.

Dr.Faubion believes that the treatment on a larger scale would only be possible if it is given a trial on a larger scale.

Women Must Be Aware of These Symptoms

Anyone who is skipping the menstrual cycle and has period issues should go to the doctor. Because there is a need to address these issues, perhaps this is an indication of premature menopause.

Ovarian dysfunction doesn’t only cause infertility. Its other effects may include ovarian infections and other diseases.

Bottom Line

When a woman finds herself skipping periods at the age of 40 and even before 40, there must be something wrong. Early menopause not only causes infertility; besides, one can not neglect its negative consequences.

Ovarian health is as crucial for you as others. Therefore, scientists are working on treatments to restore fertility and control early menopause symptoms. However, women must keep a check on their menstrual cycle and consult the doctor in frequent fluctuations.

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